Organoids through Human Emotions

Organoids are derived from human cells that have been restored to pluripotency in vitro. Today, virtually every organ and tissue in the human body has given rise to organoid formation. Building on the initial results of ORGANACT (ANR), this paper will present the mapping of the human and non-human involved in the production of organoids (donors, cerebroids, researchers, industrialists, astronauts, etc.). It will then address some of the tensions linked to these emerging entities (production, conservation, links to industry, public-private positioning...) and more specifically discuss the question of moral status. In fact, they are presented as a promise of personalized medicine, but also an innovative knowledge tool for pre-clinical and clinical research or clinical medicine. This paper will question these promises made through organoids. Are they really a tool to experiment on animals? How to deal with Assembloides ? How to apprehend chimeras that are produced with the organoids that enable their vascularization?. A thread running through this paper will be the consideration of emotions as a central element during these activities.